Names of Pain Injections Complete Informative Guide

October 30, 2026

Pain injections (also called pain management injections or interventional pain injections) are targeted treatments used by doctors to reduce inflammation, block pain signals, or support healing in specific areas of the body. They are commonly recommended for back pain, neck pain, joint arthritis, sciatica, muscle knots, and certain nerve-related conditions when oral medicines or physical therapy are not enough.

Important: This is general information only. These procedures must be performed by a qualified doctor (usually a pain specialist, orthopedist, or anesthesiologist) under image guidance. Never attempt self-injection or use any medication without medical supervision.

Most Common Types of Pain Injections

Here are the widely recognized names and categories of pain injections used in modern medical practice:

1. Epidural Steroid Injections (ESI)
Also called epidural cortisone shots or spinal steroid injections.
Medication (corticosteroid + local anesthetic) is placed in the epidural space around the spinal nerves.
Commonly used for: herniated discs, spinal stenosis, sciatica, and radiating arm or leg pain.

2. Facet Joint Injections
Injections into the small joints that connect the vertebrae in the spine.
Used for: arthritis or inflammation in the facet joints causing neck or back pain that worsens with movement.

3. Medial Branch Blocks
A diagnostic (and sometimes therapeutic) injection that targets the small nerves supplying the facet joints.
Often done before considering longer-term procedures like radiofrequency ablation.

4. Sacroiliac (SI) Joint Injections
Injection directly into the sacroiliac joint (where the spine meets the pelvis).
Used for: SI joint dysfunction, sacroiliitis, and lower back/buttock pain.

5. Trigger Point Injections
Local anesthetic (sometimes with a small amount of steroid) injected into tight “knots” in muscles.
Used for: myofascial pain, muscle spasms, and referred pain from trigger points.

6. Selective Nerve Root Blocks / Transforaminal Epidural Injections
Targeted injection near a specific spinal nerve root as it exits the spine.
Helpful for diagnosing and treating single-level nerve pain (e.g., one-sided leg or arm pain).

7. Corticosteroid (Cortisone) Joint Injections
Classic “cortisone shots” placed directly into a joint.
Common sites: knee, hip, shoulder, ankle, or smaller joints.
Used for: osteoarthritis, inflammatory arthritis, bursitis, and tendon-related inflammation.

8. Hyaluronic Acid Injections (Gel Injections / Viscosupplementation)
Thick gel-like substance injected into joints (most often the knee).
Used for: mild-to-moderate knee osteoarthritis to improve lubrication and cushioning.

9. Platelet-Rich Plasma (PRP) Injections
Concentrated platelets taken from the patient’s own blood and injected into the painful area.
Used for: certain tendon injuries, mild osteoarthritis, and soft-tissue healing support.

10. Prolotherapy (Dextrose Injections)
Injection of a concentrated sugar solution to stimulate a healing response in ligaments or tendons.
Sometimes used for chronic joint or tendon pain.

11. Peripheral Nerve Blocks
Local anesthetic (with or without steroid) injected near a specific peripheral nerve.
Examples: occipital nerve block (for certain headaches), intercostal nerve block (for rib/chest wall pain), or carpal-tunnel-related blocks.

12. Botulinum Toxin (Botox) Injections for Pain
Used in selected cases of chronic muscle-related pain or certain headache disorders (not the cosmetic version).

Other Related Terms You May Hear

  • Radiofrequency Ablation (RFA) – not a simple injection but often follows diagnostic nerve blocks; uses heat to disable pain-carrying nerves for longer relief.
  • Caudal Epidural – a type of epidural given near the tailbone.
  • Interlaminar Epidural – another approach to the epidural space.

Quick Comparison Table

Injection NameMain Target AreaTypical ConditionsUsual Duration of Relief
Epidural Steroid InjectionEpidural space around nervesSciatica, herniated disc, stenosisWeeks to several months
Facet Joint InjectionSpinal facet jointsFacet arthritisWeeks to months
SI Joint InjectionSacroiliac jointSI joint painWeeks to months
Trigger Point InjectionMuscle knotsMyofascial painDays to weeks/months
Cortisone Joint InjectionKnee/hip/shoulder etc.Osteoarthritis, bursitisWeeks to months
Hyaluronic Acid (Gel)Mainly kneeKnee osteoarthritisMonths
PRPJoints or tendonsCertain soft-tissue injuriesVariable

Frequently Asked Questions

Are all pain injections the same as cortisone shots?
No. Cortisone (corticosteroid) is one common medication, but many injections also use local anesthetics, hyaluronic acid, or the patient’s own blood products (PRP).

How long do the effects last?
It varies widely — from a few weeks to several months — depending on the type of injection, the condition being treated, and the individual patient.

Are these injections safe?
When performed by trained specialists using image guidance (X-ray or ultrasound), they are generally considered safe. Like any procedure, they carry small risks that your doctor will discuss with you.

Can I get these injections repeatedly?
Doctors usually limit the number of steroid-based injections in a given period to reduce potential side effects.

Do these injections cure the problem?
Most provide temporary relief so patients can participate in physical therapy or other treatments. They are not usually a permanent cure.

Conclusion

The most frequently used names of pain injections include epidural steroid injections, facet joint injections, sacroiliac joint injections, trigger point injections, cortisone joint shots, hyaluronic acid gel injections, PRP, and various nerve blocks. Each targets a specific source of pain and is chosen based on a proper diagnosis.

If you are dealing with ongoing pain, the best next step is to consult a qualified pain management specialist or orthopedic doctor. They can evaluate your condition, review imaging if needed, and recommend whether any of these injections are appropriate for you.

This article is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Pain injections (also called pain management injections or interventional pain injections) are targeted treatments used by doctors to reduce inflammation, block pain signals, or support healing in specific areas of the body. They are commonly recommended for back pain, neck pain, joint arthritis, sciatica, muscle knots, and certain nerve-related conditions when oral medicines or physical therapy are not enough.

Important: This is general information only. These procedures must be performed by a qualified doctor (usually a pain specialist, orthopedist, or anesthesiologist) under image guidance. Never attempt self-injection or use any medication without medical supervision.

Most Common Types of Pain Injections

Here are the widely recognized names and categories of pain injections used in modern medical practice:

1. Epidural Steroid Injections (ESI)
Also called epidural cortisone shots or spinal steroid injections.
Medication (corticosteroid + local anesthetic) is placed in the epidural space around the spinal nerves.
Commonly used for: herniated discs, spinal stenosis, sciatica, and radiating arm or leg pain.

2. Facet Joint Injections
Injections into the small joints that connect the vertebrae in the spine.
Used for: arthritis or inflammation in the facet joints causing neck or back pain that worsens with movement.

3. Medial Branch Blocks
A diagnostic (and sometimes therapeutic) injection that targets the small nerves supplying the facet joints.
Often done before considering longer-term procedures like radiofrequency ablation.

4. Sacroiliac (SI) Joint Injections
Injection directly into the sacroiliac joint (where the spine meets the pelvis).
Used for: SI joint dysfunction, sacroiliitis, and lower back/buttock pain.

5. Trigger Point Injections
Local anesthetic (sometimes with a small amount of steroid) injected into tight “knots” in muscles.
Used for: myofascial pain, muscle spasms, and referred pain from trigger points.

6. Selective Nerve Root Blocks / Transforaminal Epidural Injections
Targeted injection near a specific spinal nerve root as it exits the spine.
Helpful for diagnosing and treating single-level nerve pain (e.g., one-sided leg or arm pain).

7. Corticosteroid (Cortisone) Joint Injections
Classic “cortisone shots” placed directly into a joint.
Common sites: knee, hip, shoulder, ankle, or smaller joints.
Used for: osteoarthritis, inflammatory arthritis, bursitis, and tendon-related inflammation.

8. Hyaluronic Acid Injections (Gel Injections / Viscosupplementation)
Thick gel-like substance injected into joints (most often the knee).
Used for: mild-to-moderate knee osteoarthritis to improve lubrication and cushioning.

9. Platelet-Rich Plasma (PRP) Injections
Concentrated platelets taken from the patient’s own blood and injected into the painful area.
Used for: certain tendon injuries, mild osteoarthritis, and soft-tissue healing support.

10. Prolotherapy (Dextrose Injections)
Injection of a concentrated sugar solution to stimulate a healing response in ligaments or tendons.
Sometimes used for chronic joint or tendon pain.

11. Peripheral Nerve Blocks
Local anesthetic (with or without steroid) injected near a specific peripheral nerve.
Examples: occipital nerve block (for certain headaches), intercostal nerve block (for rib/chest wall pain), or carpal-tunnel-related blocks.

12. Botulinum Toxin (Botox) Injections for Pain
Used in selected cases of chronic muscle-related pain or certain headache disorders (not the cosmetic version).

Other Related Terms You May Hear

  • Radiofrequency Ablation (RFA) – not a simple injection but often follows diagnostic nerve blocks; uses heat to disable pain-carrying nerves for longer relief.
  • Caudal Epidural – a type of epidural given near the tailbone.
  • Interlaminar Epidural – another approach to the epidural space.

Quick Comparison Table

Injection NameMain Target AreaTypical ConditionsUsual Duration of Relief
Epidural Steroid InjectionEpidural space around nervesSciatica, herniated disc, stenosisWeeks to several months
Facet Joint InjectionSpinal facet jointsFacet arthritisWeeks to months
SI Joint InjectionSacroiliac jointSI joint painWeeks to months
Trigger Point InjectionMuscle knotsMyofascial painDays to weeks/months
Cortisone Joint InjectionKnee/hip/shoulder etc.Osteoarthritis, bursitisWeeks to months
Hyaluronic Acid (Gel)Mainly kneeKnee osteoarthritisMonths
PRPJoints or tendonsCertain soft-tissue injuriesVariable

FAQs

Are all pain injections the same as cortisone shots?
No. Cortisone (corticosteroid) is one common medication, but many injections also use local anesthetics, hyaluronic acid, or the patient’s own blood products (PRP).

How long do the effects last?
It varies widely — from a few weeks to several months — depending on the type of injection, the condition being treated, and the individual patient.

Are these injections safe?
When performed by trained specialists using image guidance (X-ray or ultrasound), they are generally considered safe. Like any procedure, they carry small risks that your doctor will discuss with you.

Can I get these injections repeatedly?
Doctors usually limit the number of steroid-based injections in a given period to reduce potential side effects.

Do these injections cure the problem?
Most provide temporary relief so patients can participate in physical therapy or other treatments. They are not usually a permanent cure.

Conclusion

The most frequently used names of pain injections include epidural steroid injections, facet joint injections, sacroiliac joint injections, trigger point injections, cortisone joint shots, hyaluronic acid gel injections, PRP, and various nerve blocks. Each targets a specific source of pain and is chosen based on a proper diagnosis.

If you are dealing with ongoing pain, the best next step is to consult a qualified pain management specialist or orthopedic doctor. They can evaluate your condition, review imaging if needed, and recommend whether any of these injections are appropriate for you.

This article is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

About the author
Noah Sullivan

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